The Breeds of Cats with the Fewest Diseases

Selection by humans is the main culprit for the persistence of certain diseases in cat breeds. Therefore, the less special variants are usually the healthiest.
The Breeds of Cats with the Fewest Diseases
Ana Díaz Maqueda

Written and verified by the biologist Ana Díaz Maqueda.

Last update: 22 December, 2022

In general, the cat breeds with the fewest diseases are those that have undergone the smallest genetic selection process, in other words, those closest to the common European cat. Anthropic selection is what causes animals to suffer from congenital pathologies that, otherwise, wouldn’t appear in nature or would not reproduce.

Unlike dogs, the selection of cats when creating new breeds has always had an aesthetic purpose. Just as many dogs have bone and joint problems due to their physical form, this doesn’t happen with cats, with rare exceptions. In the following lines, we’ll talk about the breeds of cats that don’t usually carry genes that lead to diseases.

Cats with the fewest diseases

In most cases, the breeds of cats that have congenital problems have their origin in the breeder. People who are dedicated to breeding purebreds may be tempted to cross animals with known pathologies without caring about animal welfare or the people who will acquire the feline.

Thus, many breeds of cats tend to suffer from diseases, such as the typical hypertrophic cardiomyopathy in sphinx, ragdoll or Siamese cats. In fact, the Siamese cat may be the breed with the most inherited diseases, as it’s an old variety and widely crossed between members of the same family.

Therefore, when acquiring a purebred cat, it’s essential to know about the breeder and their reputation. Another problem for breeders is that, on occasions, they breed cats with viral diseases that aren’t detected at an early stage, but that sooner or later come out. This is the case with infectious peritonitis, calicivirus or herpesvirus.

At first glance, the animals that carry the viruses are totally healthy, but due to stress and other factors, diseases can develop. Everything would be solved if the breeders avoided breeding with sick animals. We’re now going to tell you about the breeds that have fewer illnesses.

European common cat

The most disease-resistant breed of cat is the common European. Although these felids can suffer from all pathologies like any other cat, as they are not subject to continuous human selection, there’s a lower probability that they’ll carry genes that cause disease.  

In addition, the genetic variability they possess makes these cats almost immune to certain ailments or, at least, stronger ones.

A small stray cat.

British shorthair

Another fairly healthy breed of cat is the British Shorthair. This light gray feline has a more than acceptable life expectancy, exceeding 15 years. However, it may carry the gene that causes hemophilia B, a type of blood disease that causes clotting problems.

One of the cat breeds with fewer diseases.


Little known in Europe, the chausie cat breed is one of the strongest. According to the International Cat Association (TICA) , the chausie is a natural cross between a jungle cat ( Felis chaus ) and domestic cats. This mixture increases genetic variability and, with it, resistance to disease.

One of the cats with the least diseases.


The nebelung cat variety is also a breed with few health problems. Similar to the angora cat, but with a gray coat, the nebelung has a life expectancy of between 15 and 18 years.

A cat looks at the camera.

What makes these breeds more resistant?

As we’ve said repeatedly, what makes a species stronger and more resistant to disease — as well as having a low probability of developing inherited diseases — is genetic variability.

All breeds of cats, like those of dogs, are born from crossing closely related individuals, that is, consanguineous breeds. This reduces genetic variability, and negative mutations accumulate over generations.

Animals that carry deleterious recessive alleles – a copy of the gene that’s only expressed when both alleles are recessive – can leave this legacy to their offspring. If two sister cats are crossed, the probability that these alleles end up in the same individual increases.

In other words, the new cat will have only recessive copies that will be expressed and, if they give rise to an illness, it and all its offspring will suffer from it or carry that “harmful” allele. This reduction in genetic variability leads to inbreeding depression, which drastically reduces the viability of a species or breed.

When crosses between cats occur randomly and the probability of reproducing with a relative is almost nil, the genetics of the species will improve. Similarly, it also increases your survival and overall health. For all these reasons, if you want a healthy feline, you’d better buy a common European specimen.

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The contents of My Animals are written for informational purposes. They can't replace the diagnosis, advice, or treatment from a professional. In the case of any doubt, it's best to consult a trusted specialist.